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Peripheral Neuropathy: Warning Signs You Shouldn't Ignore

Key Takeaways:
  • Peripheral neuropathy causes numbness, tingling, and pain in the feet and hands
  • Diabetes is the most common cause, but many other conditions can trigger it
  • Early detection is crucial—nerve damage can be slowed but rarely reversed
  • Regular foot exams are essential for anyone at risk

What Is Peripheral Neuropathy?

Peripheral neuropathy is damage to the nerves outside your brain and spinal cord. These peripheral nerves carry signals between your body and your brain—including sensations like touch, temperature, and pain.

When these nerves are damaged, signals get disrupted. The result can be numbness, tingling, burning sensations, or pain—most commonly starting in the feet and hands.

An estimated 20 million Americans have some form of peripheral neuropathy. It's especially common in people with diabetes, affecting up to 50% of diabetics over their lifetime. But neuropathy has many causes, and anyone can develop it.

At Central Florida Foot & Ankle Institute, we see patients with neuropathy every day. The earlier it's detected, the better the outcome—which is why knowing the warning signs matters.


Warning Signs: What Does Neuropathy Feel Like?

Symptoms typically begin gradually and may be easy to dismiss at first. Pay attention if you notice:

Numbness and Reduced Sensation

  • Feeling like you're wearing socks when your feet are bare
  • Not noticing temperature changes (hot bathwater, cold surfaces)
  • Stepping on something sharp and not feeling it
  • Difficulty feeling the ground beneath your feet

Tingling and "Pins and Needles"

  • A persistent tingling sensation, like your foot "fell asleep"
  • Buzzing or vibrating feelings
  • Electric shock sensations

Burning or Shooting Pain

  • Burning sensations, especially at night
  • Sharp, stabbing pains
  • Aching or throbbing pain
  • Pain from light touch (allodynia)

Muscle Weakness and Coordination Problems

  • Difficulty lifting the front part of your foot (foot drop)
  • Feeling unsteady when walking
  • More frequent tripping or stumbling
  • Difficulty with balance, especially in the dark

Other Symptoms

  • Extreme sensitivity to touch
  • Changes in foot shape
  • Foot ulcers that heal slowly
  • Unusually sweaty or dry feet

The Danger of Ignoring Symptoms

Neuropathy isn't just uncomfortable—it's dangerous. Here's why:

Unnoticed Injuries

When you can't feel pain, small injuries go unnoticed:

  • Blisters from ill-fitting shoes
  • Cuts from stepping on something sharp
  • Burns from hot surfaces
  • Pressure sores

Infection Risk

Unnoticed wounds can become infected. In diabetics, this can lead to serious complications, including:

  • Cellulitis (skin infection)
  • Bone infection (osteomyelitis)
  • Gangrene
  • Amputation

Falls

Reduced sensation and muscle weakness increase fall risk. Falls are a leading cause of injury in older adults.

Progressive Damage

Nerve damage is often irreversible. Early intervention can slow progression, but waiting too long means losing ground you can't regain.


What Causes Peripheral Neuropathy?

Diabetes (Most Common)

High blood sugar damages blood vessels that supply nerves with nutrients and oxygen. Over time, this causes nerve damage—diabetic neuropathy. Good blood sugar control significantly reduces risk.

See our Guide for more information.

Other Medical Conditions

  • Autoimmune diseases: Lupus, rheumatoid arthritis, Guillain-Barré syndrome
  • Infections: Shingles, Lyme disease, HIV, hepatitis
  • Kidney disease: Toxin buildup damages nerves
  • Thyroid disorders: Both overactive and underactive thyroid
  • Vitamin deficiencies: B12, B6, E, and other nutrients

Medications and Toxins

  • Chemotherapy drugs
  • Certain antibiotics
  • Heavy alcohol use
  • Exposure to heavy metals or industrial chemicals

Physical Causes

  • Injuries that damage nerves
  • Pressure on nerves (carpal tunnel, tarsal tunnel)
  • Repetitive motions
  • Tumors pressing on nerves

Inherited Forms

Some types of neuropathy run in families (Charcot-Marie-Tooth disease, for example).

Idiopathic Neuropathy

In about 30% of cases, no cause is found. This is called idiopathic neuropathy.


When to See a Specialist

Don't wait for symptoms to become severe. Schedule an appointment if you:

  • Notice any numbness, tingling, or unusual sensations in your feet
  • Have burning or shooting pain in your feet
  • Experience weakness or difficulty walking
  • Have diabetes and haven't had a foot exam in the past year
  • Notice wounds on your feet that heal slowly
  • Have known risk factors for neuropathy

At Central Florida Foot & Ankle Institute, we conduct thorough neurological evaluations as part of our comprehensive foot care.


How We Diagnose Neuropathy

Comprehensive Foot Examination

We test sensation using various methods:

  • Monofilament testing (light touch)
  • Vibration perception
  • Reflexes
  • Muscle strength

Nerve Conduction Studies

Measuring how quickly electrical signals travel through nerves helps identify damage.

Blood Tests

Screening for diabetes, vitamin deficiencies, thyroid problems, and other underlying conditions.

Medical History Review

Understanding your health history, medications, and potential exposures helps identify causes.


Treatment Options

While nerve damage is often permanent, treatment can:

  • Slow or stop progression
  • Relieve symptoms
  • Prevent complications
  • Improve quality of life

Address the Underlying Cause

  • Blood sugar control for diabetics
  • Vitamin supplementation for deficiencies
  • Treating infections
  • Adjusting medications that may contribute

Pain Management

Medications:
  • Certain antidepressants (duloxetine, amitriptyline)
  • Anti-seizure medications (gabapentin, pregabalin)
  • Topical treatments (capsaicin cream, lidocaine patches)
Therapies:
  • MLS laser therapy reduces nerve pain and promotes healing
  • Physical therapy maintains strength and balance
  • TENS units provide electrical stimulation for pain relief

Protective Care

Preventing complications is crucial:

  • Daily foot inspections
  • Proper footwear
  • Regular podiatric care
  • Protecting feet from temperature extremes

Lifestyle Modifications

  • Quit smoking (smoking reduces blood flow to nerves)
  • Limit alcohol
  • Exercise regularly (improves circulation and nerve health)
  • Maintain a healthy weight

Living with Neuropathy: Daily Foot Care

If you have neuropathy, these habits protect your feet:

Inspect Daily

Check your feet every day for cuts, blisters, redness, or swelling. Use a mirror to see the bottom of your feet, or ask someone to help.

Wash and Dry Carefully

Wash feet daily with warm (not hot) water. Test temperature with your elbow, not your foot. Dry thoroughly, especially between toes.

Moisturize Wisely

Apply lotion to prevent dry, cracked skin—but not between toes, where moisture can cause infection.

Never Go Barefoot

Always wear shoes or slippers, even indoors. You won't feel if you step on something harmful.

Choose Proper Footwear

  • Wide toe boxes
  • Seamless interiors
  • No high heels
  • Properly fitted (have feet measured regularly—neuropathy can change foot shape)

Schedule Regular Checkups

See your podiatrist regularly—at least annually for mild neuropathy, more often for moderate to severe cases.


Don't Wait for Complications

Peripheral neuropathy is progressive, but it doesn't have to control your life. Early detection, proper treatment, and vigilant foot care can prevent serious complications.

At Central Florida Foot & Ankle Institute, we have extensive experience managing neuropathy and protecting feet from its consequences. Our comprehensive exams are designed to catch problems early.

📞 Schedule your neuropathy evaluation today. Your feet—and your future mobility—are worth protecting.

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